DMD #3848 ENZYME-SELECTIVE EFFECTS OF NITRIC OXIDE ON AFFINITY AND MAXIMUM VELOCITY OF VARIOUS RAT CYTOCHROMES P450 Ragini Vuppugalla and Reza Mehvar
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منابع مشابه
Enzyme-selective effects of nitric oxide on affinity and maximum velocity of various rat cytochromes P450.
Nitric oxide (NO) has recently been shown to decrease cytochrome P450 (P450) enzyme activity rapidly (< or =30 min), concentration dependently, and enzyme-selectively in the rat liver. Interestingly, among all the studied P450 enzymes, only CYP2D1 was not affected by NO donors. However, these studies were conducted using only a single concentration of the substrates, thus lacking information ab...
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تاریخ انتشار 2005